Although participation in clinical research may initially appear daunting, multiple safeguards are in place to protect volunteers. Research scientists, principal investigators, the U.S. Food and Drug Administration (FDA), and independent Institutional Review Boards (IRBs)/ethics committees rigorously oversee all studies to ensure compliance with ethical and safety standards. In addition, continuous monitoring of participants’ health status and study-related care by qualified investigators and healthcare professionals provides an added layer of protection, ensuring the highest level of safety throughout the research process.